Brain Architecture: DAC and the Hippocampus

In this tutorial we will discuss the computational principles of the Hippocampus and their possible implication in the control of behavior under the optics of the DAC architecture (Verschure, 2012; Verschure et al., 2014, 2003). I will review the mechanisms of conjunctive spatial and non-spatial coding (de Almeida et al., 2009a, 2009b, 2010; Lisman, 2007; Rennó-Costa et al., 2010); attractor dynamics (Rennó-Costa et al., 2014) and sequence processing and propose how the application of these different controls might support effective representation of tasks and efficient problem solving (Rennó-Costa et al., 2011).

 

References

 

de Almeida, L., Idiart, M., and Lisman, J.E. (2009a). The input-output transformation of the hippocampal granule cells: from grid cells to place fields. J. Neurosci. 29, 7504–7512.

 

de Almeida, L., Idiart, M., and Lisman, J.E. (2009b). A second function of gamma frequency oscillations: an E%-max winner-take-all mechanism selects which cells fire. J. Neurosci. 29, 7497–7503.

 

de Almeida, L., Idiart, M., and Lisman, J.E. (2010). The single place fields of CA3 cells: A two-stage transformation from grid cells. Hippocampus 22, 200–208.

 

Lisman, J.E. (2007). Role of the dual entorhinal inputs to hippocampus: a hypothesis based on cue/action (non-self/self) couplets. Prog. Brain Res. 163, 615–626.

 

Rennó-Costa, C., Lisman, J.E., and Verschure, P.F.M.J. (2010). The mechanism of rate remapping in the dentate gyrus. Neuron 68, 1051–1058.

 

Rennó-Costa, C., Luvizotto, A., Marcos, E., Duff, A., Sanchez-Fibla, M., and Verschure, P.F.M.J. (2011). Integrating neuroscience-based models towards an autonomous biomimetic Synthetic Forager. In 2011 IEEE International Conference on Robotics and Biomimetics, (Phuket, Thailand: IEEE), pp. 210–215.

 

Rennó-Costa, C., Lisman, J.E., and Verschure, P.F.M.J. (2014). A Signature of Attractor Dynamics in the CA3 Region of the Hippocampus. PLoS Comput. Biol. 10, e1003641.

 

Verschure, P.F.M.J. (2012). Distributed Adaptive Control: A theory of the Mind, Brain, Body Nexus. Biol. Inspired Cogn. Archit. 1, 55–72.

 

Verschure, P., Pennartz, C., and Pezzulo, G. (2014). The Why, What, Where, When and How of Goal Directed Choice: neuronal and computational principles. Proc Roy Soc B 269.

 

Verschure, P.F.M.J., Voegtlin, T., and Douglas, R.J. (2003). Environmentally mediated synergy between perception and behaviour in mobile robots. Nature 425, 620–624.